Image: National Institutes of Health (NIH) Principal Investigators Supported on NIH Research Project Grants and History of Congressional Appropriations. NIH Rock Talk Blog. Online: https://nexus.od.nih.gov/all/2015/06/29/what-are-the-chances-of-getting-funded/. Public Domain.
Fiscal Year 2019 National Institutes of Health (NIH) Funding in Massachusetts as of December 11, 2018. Data is extracted from NIH Reporter.
| 1 | Degrading Therapeutically Important Kinases Using Small Molecules | 1R01CA218278-01A1 | Gray, Nathanael Schiander | Dana-Farber Cancer Institute | $650,235 |
| 2 | Molecular Mechanisms and Therapeutic Targeting of PI3K-P110beta/PTEN Signaling in Breast Cancer and Cancer Immunity | 1R01CA233810-01 | Roberts, Thomas M | Dana-Farber Cancer Institute | $497,522 |
| 3 | Novel Therapeutic Approaches with Cdk4/6 Inhibitors for Melanoma Treatment | 1R01CA236226-01 | Sicinski, Peter | Dana-Farber Cancer Institute | $477,643 |
| 4 | RNA-Binding Proteins as Molecular Integrators that Control the Response of HGSOC to Anti-Cancer Therapies | 1R01CA226898-01A1 | Yaffe, Michael B | Massachusetts Institute of Technology | $536,497 |
| 5 | Transforming Mechanisms of Merkel Cell Polyoma Virus | 2R01CA173023-06A1 | Decaprio, James A | Dana-Farber Cancer Institute | $419,188 |
| 6 | Targeting ALK through Degradation and Allosteric Inhibitors | 2R01CA136851-10 | Gray, Nathanael Schiander | Dana-Farber Cancer Institute | $373,272 |
| 7 | Evaluating Mass Spectrometry for Intraoperative Tissue Characterization in Breast-Conserving Therapy | 5R01CA201469-04 | Agar, Nathalie | Brigham and Women’s Hospital | $393,849 |
| 8 | Personalized Vaccine for Patients with AML | 5R01CA212649-03 | Avigan, David E | Beth Israel Deaconess Medical Center | $699,542 |
| 9 | USP7 Inhibitors for the Treatment of Multiple Myeloma | 5R01CA211681-03 | Buhrlage, Sara J | Dana-Farber Cancer Inst | $510,712 |
| 10 | APOBEC Proteins as Drivers of Chromosomal Translocations in Solid Cancers | 5R01CA222598-02 | Chiarle, Roberto | Boston Children’s Hospital | $392,740 |
| 11 | Elucidating the Regulation and Function of the NF1 Tumor Suppressor | 5R01CA111754-14 | Cichowski, Karen M | Brigham and Women’s Hospital | $307,135 |
| 12 | Molecular Connections among UV Exposure; Red Hair; Nevi and Melanoma | 5R01CA193913-04 | Cui, Rutao | Boston University Medical Campus | $366,114 |
| 13 | Discovery and Optimization of Novel Mutant-Selective Allosteric Inhibitors of EGFR T790m | 5R01CA201049-04 | Eck, Michael J. | Dana-Farber Cancer Institute | $453,318 |
| 14 | Development of Diagnostic and Prognostic Tests for Esophageal Adenocarcinoma | 5R01CA208599-03 | Godfrey, Tony E. | Boston University Medical Campus | $428,383 |
| 15 | Regulation of the LIN28/LET-7 Pathway In Cancer | 5R01CA211328-03 | Gregory, Richard I. | Boston Children’s Hospital | $392,740 |
| 16 | How Does Malignancy Subvert Platelet and Megakaryocytic Biology? | 5R01CA200748-03 | Italiano, Joseph E. | Brigham and Women’s Hospital | $534,417 |
| 17 | Inhibiting Extracellular Hsp90 to Reduce Breast Cancer Metastasis | 5R01CA183119-04 | Jay, Daniel G. | Tufts University Boston | $366,114 |
| 18 | Mir-199~214 Cluster at the Crossroads of Plasticity and Malignancy in Breast Cancer | 5R01CA207322-03 | Karnoub, Antoine Elias | Beth Israel Deaconess Medical Center | $383,865 |
| 19 | Interplay of Mammary Luminal Cells and Environmental Factors in Establishing p53-Deficient Premalignant Field | 5R01CA222560-02 | Li, Zhe | Brigham and Women’s Hospital | $363,522 |
| 20 | Polyploidy; Aneuploidy; and Genome Stability | 5R01CA213404-21 | Pellman, David S | Dana-Farber Cancer Institute | $388,303 |
| 21 | Systemic RNA Delivery to Tumors | 5R01CA200900-04 | Shi, Jinjun | Brigham and Women’s Hospital | $526,391 |
| 22 | Lipid-Dendrimer Micellar Nanocarriers for SIRNA/Drug Co-Delivery in MDR Cancer | 5R01CA200844-04 | Torchilin, Vladimir P | Northeastern University | $339,188 |
| 23 | Reprogramming the Tumor Microenvironment via Self-Amplified RNA (Safer) Circuits | 5R01CA206218-04 | Weiss, Ron | Massachusetts Institute of Technology | $533,720 |
| 24 | Dietary Control of Stem Cells in Physiology and Cancer | 5R01CA211184-03 | Yilmaz, Omer | Massachusetts Institute of Technology | $397,201 |
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